FIGURE

Fig. 5

ID

ZDB-FIG-180827-17

Publication

Ferrero et al., 2018 - Embryonic Microglia Derive from Primitive Macrophages and Are Replaced by cmyb-Dependent Definitive Microglia in Zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 5

The Transcription Factor cmyb Is Required for the Establishment of Adult MG

(A) Scheme of the hematopoietic cell transplantation experiments performed to circumvent the lethality of c-myb^null animals due to the lack of definitive hematopoiesis.

(B) GFP immunostaining performed on adult brain sections from wild-type controls (upper panels) and rescued cmyb^null mutants (lower panels), demonstrating a complete absence of host-derived GFP⁺ MG in the cmyb mutants (left panels), as well as the presence of GFP⁻ donor-derived L-plastin⁺ hematopoietic cells (fuchsia, middle panels). The right panels show a merge of both fluorescent channels (n = 4). Scale bar: 50 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Cell Rep.