FIGURE

Fig. S9

ID

ZDB-FIG-180516-26

Publication

Ojeda Naharros et al., 2017 - Loss-of-function of the ciliopathy protein Cc2d2a disorganizes the vesicle fusion machinery at the periciliary membrane and indirectly affects Rab8-trafficking in zebrafish photoreceptors

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Fig. S9

Retinae of rhod:mCherry-rab8a are structurally healthy.

(A) Transmission electron microscopy image of a wild-type 5dpf tg(rhod:mCherry-rab8a) retina. The retinal structure remains normal and extension of outer segments is unaffected. Variable accumulation of membrane-bound structures in inner segment regions is observed in a subset of PRs as a consequence of the overexpression of the transgenic construct (absent in A’, present in A”). Scale bars: 10 μm in A and 2 μm in A’ and A”. OS outer segment, m mitochondria, N nucleus, v vesiculo-tubular structures.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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