FIGURE

Fig. S4

ID
ZDB-FIG-170209-55
Publication
Noack Watt et al., 2016 - The Roles of RNA Polymerase I and III Subunits Polr1c and Polr1d in Craniofacial Development and in Zebrafish Models of Treacher Collins Syndrome
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Fig. S4

The migratory NCC population is not undergoing apoptosis in polr1c and polr1d mutant embryos.

(A-D) TUNEL staining in sox10:gfp embryos shows increased cell death in mutant embryos which does not co-localize with the migratory NCC population. At 24 hpf, increased cell death can be seen in the neuroepithelial region of polr1c-/- and polr1d-/- embryos. (E-F) At 48 hpf, increased cell death can be observed in regions of the brain and eye of mutant embryos, but not within the pharyngeal arches. Scale bar = 200 μm.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Observed In:
Stage: Prim-5

Phenotype Detail
Acknowledgments
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