FIGURE

Fig. 8

ID
ZDB-FIG-170209-43
Publication
Noack Watt et al., 2016 - The Roles of RNA Polymerase I and III Subunits Polr1c and Polr1d in Craniofacial Development and in Zebrafish Models of Treacher Collins Syndrome
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Fig. 8

tp53 inhibition ameliorates cartilage anomalies in polr1d-/- mutant embryos in a dosage-dependent manner.

(A-D) Alcian blue staining of cartilage in an allelic series of polr1d and tp53 mutant embryos. Dosage-dependent improvement in cartilage development is particularly noticeable in the jaw (E-H), elements of the viscerocranium (I-L), and more specifically the ceratohyal (G-L). Abbreviations: M, Meckel’s cartilage; pq, palatoquadrate; ch, ceratohyal; cb, ceratobranchial. Scale bar = 200 μm.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Observed In:
Stage: Day 5

Phenotype Detail
Acknowledgments
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