FIGURE

Fig. 8

ID

ZDB-FIG-140602-19

Publication

Zannino et al., 2014 - prdm12b specifies the p1 progenitor domain and reveals a role for V1 interneurons in swim movements

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Fig. 8

Increased replication of OPCs in prdm12b deficient embryos. (A–I) olig2:egfp Expression in wild type (A–C), control MO-injected (D–F), or PTB MO-injected (G–I) embryos. (J) Quantification of embryos with reduced numbers of olig2:egfp⁺ cells. (K) Quantification of olig2:egfp⁺ cells per embryo at 72 hp. (L–O) Cross sections of wild type (L, M) and PTB MO-injected (N, O) Tg(olig2:egfp) embryos labeled with anti-BrdU. (P) Quantification of the number of olig2:egfp⁺/BrdU⁺ cells per section. Scale bars are 35 μm (A–I) or 17 μm (L, M). The neural tube is outlined with dotted line in L, M. Arrows indicate olig2:egfp/BrdU double positive cells.

Expression Data

Gene:	EGFP
Fish:	vu12Tg vu12Tg + MO1-prdm12b
Knockdown Reagent:	MO1-prdm12b
Anatomical Terms:	hindbrain glioblast (sensu Vertebrata) hindbrain oligodendrocyte rhombomere 5 glioblast (sensu Vertebrata) rhombomere 6 glioblast (sensu Vertebrata)
Stage Range:	Prim-25 to Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	vu12Tg + MO1-prdm12b
Knockdown Reagent:	MO1-prdm12b
Observed In:	glioblast (sensu Vertebrata) hindbrain oligodendrocyte oligodendrocyte progenitor proliferation
Stage Range:	Prim-25 to Protruding-mouth

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 390, Zannino, D.A., Downes, G.B., Sagerström, C.G., prdm12b specifies the p1 progenitor domain and reveals a role for V1 interneurons in swim movements, 247-60, Copyright (2014) with permission from Elsevier. Full text @ Dev. Biol.