FIGURE

Fig. 6

ID
ZDB-FIG-130826-40
Publication
Huang et al., 2013 - Igf Signaling is Required for Cardiomyocyte Proliferation during Zebrafish Heart Development and Regeneration
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Fig. 6

Igf signaling is required for heart regeneration.

Wild type fish were treated DMSO (A) (n = 6) or the Igf1r inhibitor NVP-AEW541 (n = 7) (B and C) from 2–30 dpa. AFOG staining was performed at 30 dpa to detect collagen (blue) and fibrin (red) deposition. The dashed line marks the regenerating area. Scale bar = 100 μm. ia: injured area. (D) Quantification of scar area normalized to ventricle area in DMSO and NVP-AEW541 treated hearts. A significant increase (*p<0.05) in scar/ventricular area ratio was detected in NVP-AEW541 treated hearts.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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