FIGURE

Fig. S7

ID

ZDB-FIG-121030-28

Publication

Hinits et al., 2012 - Zebrafish Mef2ca and Mef2cb are essential for both first and second heart field cardiomyocyte differentiation

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Fig. S7

Mef2ca and Mef2cb are expressed in hand2 knockdown embryos.
In situ mRNA hybridisation for mef2ca (A) and mef2cb (B) in hearts of control and hand2 MO zebrafish embryos, shown in dorsal view, anterior to top. A and B. Hearts of hand2morphants show cardia bifida phenotype (arrows). CMs on both sides of the midline express both mef2ca and mef2cb. Expression of mef2ca in pharyngeal arches CNC (cranial neural crest) is marked with asterisks. Scale = 100 μm.

Expression Data

Genes:	mef2ca mef2cb
Fish:	WT WT + MO2-hand2
Knockdown Reagent:	MO2-hand2
Anatomical Terms:	cranial neural crest heart primordium heart rudiment pharyngeal arch
Stage:	20-25 somites

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO2-hand2
Knockdown Reagent:	MO2-hand2
Observed In:	cardiac muscle cell heart formation heart rudiment
Stage:	20-25 somites

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 369(2), Hinits, Y., Pan, L., Walker, C., Dowd, J., Moens, C.B., and Hughes, S.M., Zebrafish Mef2ca and Mef2cb are essential for both first and second heart field cardiomyocyte differentiation, 199-210, Copyright (2012) with permission from Elsevier. Full text @ Dev. Biol.