FIGURE

Fig. S6

ID
ZDB-FIG-120426-22
Publication
Cha et al., 2012 - Chemokine Signaling Directs Trunk Lymphatic Network Formation along the Preexisting Blood Vasculature
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Fig. S6

(related to Figure 6). Ectopic expression of Cxcl12b induces abnormal migration of LECs

(A-D) Confocal images of trunk vessels in a 5 dpf Tg(fli-EGFP)y1 embryos expressing TagRFP-T and Cxcl12b in a subset of vISV endothelial cells. A red box in A indicates magnified area showing in B to D. (B) Green channel only. (C) Merged image. (D) Red channel only. Magenta arrowheads indicate ectopic Cxcl12b-expressing vISV endothelial cells. White arrowheads point to an adjacent ectopic vISV-aligned lymphatic segment.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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Reprinted from Developmental Cell, 22(4), Cha, Y.R., Fujita, M., Butler, M., Isogai, S., Kochhan, E., Siekmann, A.F., and Weinstein, B.M., Chemokine Signaling Directs Trunk Lymphatic Network Formation along the Preexisting Blood Vasculature, 824-836, Copyright (2012) with permission from Elsevier. Full text @ Dev. Cell