| ZFIN ID: ZDB-FIG-110712-77 |
Gregory-Evans et al., 2011
- Gene-specific differential response to anti-apoptotic therapies in zebrafish models of ocular coloboma.
Molecular Vision
17:1473-1484
Fig. 7 Effect of caspase inhibition on survival and optic fissure closure. A: Mean survival of gup mutant embryos with no treatment or with either diferuloylmethane, zVAD-fmk or control inhibitor zFA-fmk. n=30 for each group, mean±SEM (*p<0.001). B: Wildtype (wt) larval phenotype at 8 dpf. C: Phenotype of gup mutants treated with 5 μM diferuloylmethane. D: Phenotype of gup mutant embryos treated with 300 μM zVAD-fmk. E: Phenotype of gup mutants treated with 300 μM zFA-fmk. Arrows indicate the position of the coloboma. Size bar in left panels=200 μm; size bar in right panels=500 μm. |
Gene Expression Details
No data available
Antibody Labeling Details
No data available
Phenotype Details
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