ZFIN ID: ZDB-FISH-150901-29413
Fish name: lamb1am189/m189
Genotype: lamb1am189/m189
Targeting Reagent: none
HUMAN DISEASE MODELED by lamb1am189/m189
Human Disease Conditions Citations
coloboma standard conditions (2)
GENE EXPRESSION
Gene expression in lamb1am189/m189
RNA expression No data available
Protein expression No data available
Reporter gene expression No data available
PHENOTYPE
Phenotype in lamb1am189/m189
Phenotype Conditions Figures
closure of optic fissure decreased process quality, abnormal control Fig. 2 with imageFig. 3 with image from Gregory-Evans et al., 2011
closure of optic fissure process quality, ameliorated chemical treatment by environment: Z-Val-Ala-Asp(OMe)-CH2F Fig. 2 with imageFig. 3 with image from Gregory-Evans et al., 2011
closure of optic fissure process quality, ameliorated chemical treatment by environment: curcumin Fig. 2 with imageFig. 3 with image from Gregory-Evans et al., 2011
eye decreased size, abnormal standard conditions Fig. 8 from Moosajee et al., 2008
eye lacks all parts of type lens, abnormal chemical treatment by environment: curcumin Fig. 5 with image from Gregory-Evans et al., 2011
eye morphology, abnormal standard conditions Fig. 9 from Moosajee et al., 2008
eye shape, abnormal standard conditions Fig. 8 from Moosajee et al., 2008
eye apoptotic process increased occurrence, abnormal control Fig. 3 with imageFig. 5 with image from Gregory-Evans et al., 2011
eye apoptotic process occurrence, ameliorated chemical treatment by environment: Z-Val-Ala-Asp(OMe)-CH2F Fig. 3 with image from Gregory-Evans et al., 2011
eye apoptotic process occurrence, ameliorated chemical treatment by environment: curcumin Fig. 3 with imageFig. 5 with image from Gregory-Evans et al., 2011
lens decreased size, abnormal standard conditions Fig. 8 from Moosajee et al., 2008
lens displaced, abnormal standard conditions Fig. 8Fig. 9 from Moosajee et al., 2008
lens hypoplastic, abnormal standard conditions Fig. 9 from Moosajee et al., 2008
lens malformed, abnormal standard conditions Fig. 9 from Moosajee et al., 2008
lens structure, abnormal standard conditions Fig. 9 from Moosajee et al., 2008
lens development in camera-type eye arrested, abnormal chemical treatment by environment: curcumin Fig. 5 with image from Gregory-Evans et al., 2011
optic fissure closure incomplete, abnormal standard conditions Fig. 8 from Moosajee et al., 2008
optic fissure increased width, abnormal control Fig. 2 with imageFig. 3 with image from Gregory-Evans et al., 2011
optic fissure width, ameliorated chemical treatment by environment: curcumin Fig. 2 with imageFig. 3 with image from Gregory-Evans et al., 2011
optic fissure width, ameliorated chemical treatment by environment: Z-Val-Ala-Asp(OMe)-CH2F Fig. 2 with imageFig. 3 with image from Gregory-Evans et al., 2011
pericardium edematous, abnormal standard conditions Fig. 8 from Moosajee et al., 2008
retina layer formation disrupted, abnormal standard conditions Fig. 8 from Moosajee et al., 2008
swim bladder inflation arrested, abnormal standard conditions Fig. 8 from Moosajee et al., 2008
whole organism decreased length, abnormal standard conditions Fig. 8 from Moosajee et al., 2008
whole organism decreased life span, abnormal control Fig. 7 with image from Gregory-Evans et al., 2011
whole organism life span, ameliorated chemical treatment by environment: Z-Val-Ala-Asp(OMe)-CH2F Fig. 7 with image from Gregory-Evans et al., 2011
whole organism life span, ameliorated chemical treatment by environment: curcumin Fig. 7 with image from Gregory-Evans et al., 2011
whole organism apoptotic process increased occurrence, abnormal control Fig. 3 with image from Gregory-Evans et al., 2011
whole organism apoptotic process occurrence, ameliorated chemical treatment by environment: curcumin Fig. 3 with image from Gregory-Evans et al., 2011
whole organism apoptotic process occurrence, ameliorated chemical treatment by environment: Z-Val-Ala-Asp(OMe)-CH2F Fig. 3 with image from Gregory-Evans et al., 2011

CITATIONS  (5)