FIGURE

Fig. 3

ID

ZDB-FIG-091214-57

Publication

Rieger et al., 2009 - Cadherin-2 controls directional chain migration of cerebellar granule neurons

Other Figures

All Figure Page

Back to All Figure Page

Fig. 3

Cadherin-2 regulates coherence of cerebellar GC migration.

(A–J) Maximum intensity projections of individual time-lapse stacks show GC migration in the right cerebellar lobe of gata1:GFP WT and gata1:GFP/pac^-/-R-embryos. Cell tracings reveal that GCs in WT cerebella (A–E) migrate collectively toward the MHB, whereas individually migrating pac^-/-R GCs (F–J) follow deviant paths (compare also Video S4 and Video S5). Plotting the migratory tracks from start to end point (K–N) shows a highly coherent and directional migration of WT GCs (K, L) in contrast to pac^-/-R GCs (M, N) (e.g., compare dark blue and red tracks in L and N). cb, cerebellum; MHB, midbrain-hindbrain boundary; URL, upper rhombic lip.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Biol.