FIGURE

Fig. 11

ID

ZDB-FIG-080804-20

Publication

Budi et al., 2008 - Embryonic requirements for ErbB signaling in neural crest development and adult pigment pattern formation

Other Figures

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Fig. 11

picasso mutant embryos have defects in neural crest morphogenesis. (A,A′) crestin⁺ cells form segmentally arranged clusters prior to ganglion formation in wild-type embryos (e.g. arrow in A) but appear to migrate past their normal target sites in picasso mutant embryos (e.g. arrowhead in A′). (B,B′) mitfa⁺ cells in wild-type exhibit some segmental patterning and a defect in picasso mutants similar to that of crestin⁺ cells. (C,C′) dct⁺ melanoblast distributions do not differ consistently between wild-type and picasso mutant embryos. (D,D′) Anti-Hu immunoreactivity shows dorsal root ganglia (e.g. arrow in D) and sympathetic ganglia (e.g. arrowhead in D) in wild-type larvae but their absence in picasso mutants. Scale bar: in A′, 800 μm for A-C′; in D′, 600 μm for D-D′.

Expression Data

Genes:	crestin dct mitfa
Fish:	WT erbb3b^{wpr2e2/wpr2e2}
Anatomical Terms:	melanoblast neural crest
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	erbb3b^{wpr2e2/wpr2e2}
Observed In:	dorsal root ganglion neural crest cell migration sympathetic chain ganglion
Stage Range:	Prim-5 to Days 7-13

Phenotype Detail

Acknowledgments

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