| ZFIN ID: ZDB-FIG-071219-29 |
Gribble et al., 2007
- Regulation and function of Dbx genes in the zebrafish spinal cord.
Developmental dynamics : an official publication of the American Association of Anatomists
236(12):3472-3483
Full text @ Dev. Dyn.
EXPRESSION / LABELING:
| Genes: | |
|---|---|
| Fish: | |
| Condition: | |
| Anatomical Term: | |
| Stage: | Prim-5 |
PHENOTYPE:
| Fish: | |
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| Condition: | |
| Observed In: | |
| Stage: | Prim-5 |
Fig. 4 en1b+ and evx1+ interneurons increase in cyclopamine-treated embryos. A-D: Lateral whole-mount views of subtype-specific postmitotic marker are shown with rostral to the left at 24 hours postfertilization (hpf). A-F: en1b+ (A,C,E) and pax2.1+ (B,D,F) interneurons are increased in cyclopamine-treated embryos. Error bars represent SEM. G,H: Representative sections of green fluorescent protein (GFP) expression in Tg(elavl3:EGFP)zf8 embryos are shown. There is no change in the number of Hu-positive neurons after cyclopamine treatment. |
Gene Expression Details
| Gene | Antibody | Fish | Conditions | Stage | Anatomy | Assay |
|---|---|---|---|---|---|---|
| en1b | AB | control | Prim-5 | unspecified | ISH | |
| AB | chemical treatment: Cyclopamine | Prim-5 | unspecified | ISH | ||
| pax2a | AB | control | Prim-5 | unspecified | ISH | |
| AB | chemical treatment: Cyclopamine | Prim-5 | unspecified | ISH |
Antibody Labeling Details
No data available
Phenotype Details
| Fish | Conditions | Stage | Phenotype |
|---|---|---|---|
| AB | chemical treatment: Cyclopamine | Prim-5 | spinal cord interneuron increased amount, abnormal |
| knu3Tg | control | Prim-5 | neuron amount, normal |
| knu3Tg | chemical treatment: Cyclopamine | Prim-5 | neuron amount, normal |
| Acknowledgments: | This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dev. Dyn. |
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