ZFIN ID: ZDB-FIG-071219-29
Gribble et al., 2007 - Regulation and function of Dbx genes in the zebrafish spinal cord. Developmental dynamics : an official publication of the American Association of Anatomists   236(12):3472-3483 Full text @ Dev. Dyn.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Condition:
Anatomical Term:
Stage: Prim-5
PHENOTYPE:
Fish:
Condition:
Observed In:
Stage: Prim-5

Fig. 4 en1b+ and evx1+ interneurons increase in cyclopamine-treated embryos. A-D: Lateral whole-mount views of subtype-specific postmitotic marker are shown with rostral to the left at 24 hours postfertilization (hpf). A-F: en1b+ (A,C,E) and pax2.1+ (B,D,F) interneurons are increased in cyclopamine-treated embryos. Error bars represent SEM. G,H: Representative sections of green fluorescent protein (GFP) expression in Tg(elavl3:EGFP)zf8 embryos are shown. There is no change in the number of Hu-positive neurons after cyclopamine treatment.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
en1b AB control Prim-5 unspecified ISH
AB chemical treatment: Cyclopamine Prim-5 unspecified ISH
pax2a AB control Prim-5 unspecified ISH
AB chemical treatment: Cyclopamine Prim-5 unspecified ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
AB chemical treatment: Cyclopamine Prim-5 spinal cord interneuron increased amount, abnormal
knu3Tg control Prim-5 neuron amount, normal
knu3Tg chemical treatment: Cyclopamine Prim-5 neuron amount, normal
Acknowledgments:
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dev. Dyn.