FIGURE SUMMARY
Title

Novel Anti-Obesity Properties of Palmaria mollis in Zebrafish and Mouse Models

Authors
Nakayama, H., Shimada, Y., Zang, L., Terasawa, M., Nishiura, K., Matsuda, K., Toombs, C., Langdon, C., Nishimura, N.
Source
Full text @ Nutrients

Post-administration of Palmaria mollis (PM) in overfed diet-induced obese (DIO)-zebrafish. (A) Schedule of PM supplementation in zebrafish Experiment 1. Overfeeding and PM supplementation started on week 0 and 2, respectively. (B) Body weight change during Experiment 1. (C) Volume of visceral adipose tissues (VAT) in week 6. (DE) PM suppressed increases in plasma triacylglycerol (TG; D) and low-density lipoprotein cholesterol (LDL-C; E) in DIO-zebrafish. (F) Lipid accumulation in liver tissues. Lipid droplets (red spots) increased in DIO-zebrafish compared to control. Lower graph indicates the quantification of red signals. * p < 0.05, ** p < 0.01 vs. control. n = 7–10, error bars indicate standard deviations (SD).

PM effects on insulin-EGFP expression in zebrafish. *p < 0.05, n = 5, error bars indicate SD.

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Acknowledgments
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