TALEN

TALEN1-gjd1a

ID
ZDB-TALEN-170822-3
Name
TALEN1-gjd1a
Previous Names
None
Target
Target Sequence 1
5' - GAGAGTCATAAGCGCGGCA - 3'
ZFIN BLAST NCBI BLAST Ensembl
Target Sequence 2
5' - CCAGCAACCTCTCCAATAT - 3'
ZFIN BLAST NCBI BLAST Ensembl
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
fh436 gjd1a
Expression
Gene expression in Wild Types + TALEN1-gjd1a
No data available
Phenotype
Phenotype resulting from TALEN1-gjd1a
No data available
Phenotype of all Fish created by or utilizing TALEN1-gjd1a
Phenotype Fish Conditions Figures
Mauthner neuron chemical synaptic transmission increased frequency, abnormal gjd1afh436/fh436 standard conditions Figure 4 with image from Lasseigne et al., 2021
Mauthner neuron synapse absent, abnormal gjd1afh436/fh436 standard conditions Fig. 1 from Shah et al., 2015
Mauthner neuron chemical synaptic transmission normal occurrence, ameliorated gjd1afh436/fh436 chemical treatment by environment: 6-Cyano-7-nitroquinoxaline-2,3-dione, chemical treatment by environment: 2-amino-5-phosphonopentanoic acid Figure 4 with image from Lasseigne et al., 2021
Mauthner neuron cell communication by electrical coupling decreased frequency, abnormal gjd1afh436/fh436 standard conditions Figure 4 with image from Lasseigne et al., 2021
spinal cord interneuron synapse assembly arrested, abnormal gjd1afh436/+; gjd1afh360/+; zf206Et (AB/TU) standard conditions Fig. 1 with image from Miller et al., 2017
spinal cord interneuron synapse absent, abnormal gjd1afh436/+; gjd1afh360/+; zf206Et (AB/TU) standard conditions Fig. 1 with image from Miller et al., 2017
Mauthner neuron synapse assembly arrested, abnormal gjd1afh436/+; gjd1afh360/+; zf206Et (AB/TU) standard conditions Fig. 1 with image from Miller et al., 2017
Mauthner neuron synapse ab3-gjd2 labeling absent, abnormal gjd1afh436/+; gjd1afh360/+; zf206Et (AB/TU) standard conditions Fig. 1 with image from Miller et al., 2017
Mauthner neuron synapse absent, abnormal gjd1afh436/+; gjd1afh360/+; zf206Et (AB/TU) standard conditions Fig. 1 with image from Miller et al., 2017
spinal cord interneuron synapse ab3-gjd2 labeling absent, abnormal gjd1afh436/+; gjd1afh360/+; zf206Et (AB/TU) standard conditions Fig. 1 with image from Miller et al., 2017
Mauthner neuron dendrite gjd1a expression decreased amount, abnormal gjd1afh436/fh436; zf206Et standard conditions Figure 2 with image from Lasseigne et al., 2021
Mauthner neuron dendrite gjd2a expression decreased amount, abnormal gjd1afh436/fh436; zf206Et standard conditions Figure 2 with image from Lasseigne et al., 2021
Mauthner neuron synapse ab1-tjp1 labeling decreased amount, abnormal gjd1afh436/fh436; zf206Et standard conditions Figure 2 with image from Lasseigne et al., 2021
Mauthner neuron protein localization to synapse disrupted, abnormal gjd1afh436/fh436; zf206Et standard conditions Figure 2 with image from Lasseigne et al., 2021
Mauthner neuron synapse gjd1a expression decreased amount, abnormal gjd1afh436/fh436; zf206Et standard conditions Figure 2 with image from Lasseigne et al., 2021
Mauthner neuron synapse gjd2a expression decreased amount, abnormal gjd1afh436/fh436; zf206Et standard conditions Figure 2 with image from Lasseigne et al., 2021
Mauthner neuron dendrite ab1-tjp1 labeling decreased amount, abnormal gjd1afh436/fh436; zf206Et standard conditions Figure 2 with image from Lasseigne et al., 2021
afferent neuron synapse Ab1-gjd2a labeling decreased amount, abnormal gjd1afh436/fh436; zf206Et (AB/TU) standard conditions Fig. 5 with image from Miller et al., 2017
afferent neuron synapse ab3-gjd2 labeling decreased amount, abnormal gjd1afh436/fh436; zf206Et (AB/TU) standard conditions Fig. 3 with image from Miller et al., 2017
cranial nerve VIII synapse Ab1-gjd1a labeling absent, abnormal gjd1afh436/fh436; zf206Et (AB/TU) standard conditions Fig. 5 with image from Miller et al., 2017
spinal cord interneuron synapse assembly arrested, abnormal gjd1afh436/fh436; zf206Et (AB/TU) standard conditions Fig. 3 with image from Miller et al., 2017
spinal cord interneuron synapse absent, abnormal gjd1afh436/fh436; zf206Et (AB/TU) standard conditions Fig. 3 with image from Miller et al., 2017
Mauthner neuron synapse assembly arrested, abnormal gjd1afh436/fh436; zf206Et (AB/TU) standard conditions Fig. 3 with image from Miller et al., 2017
cranial nerve VIII synapse ab3-gjd2 labeling decreased amount, abnormal gjd1afh436/fh436; zf206Et (AB/TU) standard conditions Fig. 3 with image from Miller et al., 2017
afferent neuron synapse decreased amount, abnormal gjd1afh436/fh436; zf206Et (AB/TU) standard conditions Fig. 3 with image from Miller et al., 2017
Mauthner neuron synapse Ab1-gjd1a labeling absent, abnormal gjd1afh436/fh436; zf206Et (AB/TU) standard conditions Fig. 5 with image from Miller et al., 2017
afferent neuron synapse assembly decreased occurrence, abnormal gjd1afh436/fh436; zf206Et (AB/TU) standard conditions Fig. 3 with image from Miller et al., 2017
Mauthner neuron synapse ab3-gjd2 labeling absent, abnormal gjd1afh436/fh436; zf206Et (AB/TU) standard conditions Fig. 3 with image from Miller et al., 2017
Mauthner neuron synapse Ab1-gjd2a labeling absent, abnormal gjd1afh436/fh436; zf206Et (AB/TU) standard conditions Fig. 5 with image from Miller et al., 2017
Mauthner neuron synapse non-functional, abnormal gjd1afh436/fh436; zf206Et (AB/TU) standard conditions Fig. 4 with image from Miller et al., 2017
Mauthner neuron synapse absent, abnormal gjd1afh436/fh436; zf206Et (AB/TU) standard conditions Fig. 3 with image from Miller et al., 2017
spinal cord interneuron synapse ab3-gjd2 labeling absent, abnormal gjd1afh436/fh436; zf206Et (AB/TU) standard conditions Fig. 3 with image from Miller et al., 2017
startle response latency, abnormal gjd1afh436/fh436; zf206Et (AB/TU) standard conditions Fig. 8 with image from Miller et al., 2017
cranial nerve VIII synapse Ab1-gjd2a labeling decreased amount, abnormal gjd1afh436/fh436; zf206Et (AB/TU) standard conditions Fig. 5 with image from Miller et al., 2017
startle response process quality, abnormal gjd1afh436/fh436; zf206Et (AB/TU) standard conditions Fig. 8 with image from Miller et al., 2017
spinal cord interneuron synapse Ab1-gjd2a labeling absent, abnormal gjd1afh436/fh436; zf206Et (AB/TU) standard conditions Fig. 5 with image from Miller et al., 2017
spinal cord interneuron synapse Ab1-gjd1a labeling absent, abnormal gjd1afh436/fh436; zf206Et (AB/TU) standard conditions Fig. 5 with image from Miller et al., 2017
afferent neuron synapse Ab1-gjd1a labeling absent, abnormal gjd1afh436/fh436; zf206Et (AB/TU) standard conditions Fig. 5 with image from Miller et al., 2017
Mauthner neuron dendrite gjd2a expression decreased amount, abnormal gjd1afh436/fh436; gjd2afh437/fh437; zf206Et standard conditions Figure 2 with image from Lasseigne et al., 2021
Mauthner neuron dendrite gjd1a expression decreased amount, abnormal gjd1afh436/fh436; gjd2afh437/fh437; zf206Et standard conditions Figure 2 with image from Lasseigne et al., 2021
Mauthner neuron protein localization to synapse disrupted, abnormal gjd1afh436/fh436; gjd2afh437/fh437; zf206Et standard conditions Figure 2 with image from Lasseigne et al., 2021
Mauthner neuron synapse gjd2a expression decreased amount, abnormal gjd1afh436/fh436; gjd2afh437/fh437; zf206Et standard conditions Figure 2 with image from Lasseigne et al., 2021
Mauthner neuron synapse gjd1a expression decreased amount, abnormal gjd1afh436/fh436; gjd2afh437/fh437; zf206Et standard conditions Figure 2 with image from Lasseigne et al., 2021
Citations
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