ZFIN Image: Ren et al., 2024, Figure 5

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Figure Caption

Figure 5

Dhx38 regulates the alternative splicing of some genes involved in DNA damage repair: (A) Increased rate of transcripts with IR or ES among DNA repair in inner ears of dhx38 mutant embryos, as detected by PCR at 36 hpf. (B) The alternative splicing of these genes at 42 hpf. (C) The statistical data are presented as the mean ± SD of the PSI values at 36 hpf and 42 hpf from three biological replicates. PSI, percent splicing in. (D) The mRNA expression levels of some genes in inner ears of sibling and dhx38⁻^/− mutant embryos with DNA repair, as detected using RT-PCR. The data are presented as the mean ± SD. ns, p > 0.05; *, p < 0.05; **, p < 0.01; ***, p < 0.001.

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Acknowledgments

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