Gene

eme1

ID
ZDB-GENE-030131-3191
Name
essential meiotic structure-specific endonuclease 1
Symbol
eme1 Nomenclature History
Previous Names
  • fc30c07
  • wu:fc30c07
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to contribute to crossover junction endodeoxyribonuclease activity. Predicted to be involved in DNA metabolic process and intra-S DNA damage checkpoint. Predicted to localize to Holliday junction resolvase complex and nuclear chromatin. Orthologous to human EME1 (essential meiotic structure-specific endonuclease 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With eme1 Human Ortholog
No data available
Associated With eme1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR006166 ERCC4 domain
Family IPR033310 Mms4/EME1/EME2
Homologous_superfamily IPR042530 EME1/EME2, C-terminal domain
Homologous_superfamily IPR043086 EME1, nuclease domain, subdomain 1
Homologous_superfamily IPR043087 EME1, nuclease domain, subdomain 2
Domain Details Per Protein
Protein Length EME1/EME2, C-terminal domain EME1, nuclease domain, subdomain 1 EME1, nuclease domain, subdomain 2 ERCC4 domain Mms4/EME1/EME2
UniProtKB:E7F6N8
InterPro PDB
556
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
aberrant processed transcript eme1-204 (1)
Ensembl
Havana 760 nt
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA eme1-202 (1)
Ensembl
Havana 2522 nt
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA eme1-203 (1)
Ensembl
Havana 825 nt
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA eme1-205 (1)
Ensembl
Havana 847 nt
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
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