Gene

slx4

ID
ZDB-GENE-050208-359
Name
SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
Symbol
slx4 Nomenclature History
Previous Names
  • btbd12
  • fancp (1)
  • si:dkey-44g23.4
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Is predicted to enable enzyme binding activity. Involved in interstrand cross-link repair; meiotic DNA double-strand break processing; and resolution of meiotic recombination intermediates. Acts upstream of or within gall bladder development and hepatic duct development. Predicted to be located in membrane and nucleus. Predicted to be integral component of membrane. Predicted to be part of Slx1-Slx4 complex. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group P. Orthologous to human SLX4 (SLX4 structure-specific endonuclease subunit).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
7 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With slx4 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Fanconi anemia complementation group P Alliance Fanconi anemia, complementation group P 613951
Associated With slx4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000210 BTB/POZ domain
Domain IPR013087 Zinc finger C2H2-type
Family IPR018574 Structure-specific endonuclease subunit Slx4
Homologous_superfamily IPR011333 SKP1/BTB/POZ domain superfamily
Domain Details Per Protein
Protein Length BTB/POZ domain SKP1/BTB/POZ domain superfamily Structure-specific endonuclease subunit Slx4 Zinc finger C2H2-type
UniProtKB:F1QGW3 117
UniProtKB:A0A2R8QIP4 1712
UniProtKB:F1QPU2 1719
UniProtKB:F1QUW5 208
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations