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Figure 5

Metabolic dyshomeostasis in VDD AT. (A) Elevated expression of lipid transporters in VDD liver 6 mpf. Decreased expression of fabp11a in VDD AT 6 mpf. (B) Elevated expression of lypolitic factors in VDD liver 6 mpf, with a decrease in lipea and lipeb in VDD AT. (C) Greater abundance of erk1/2 protein in VDD liver 6 mpf, with a decreased in p-erk1/2. (D) Suppression of mitochondrial biogenesis in VDD AT compared to VDD liver 6 mpf. (E) Elevated expression of lipogenic factors in VDD liver 6 mpf. Elevated expression of pparg and srebf1 in VDD AT 6 mpf with a decrease in pparaa and cebpa. *See also Figure S3.

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