FIGURE

Fig. 4

ID

ZDB-FIG-260702-128

Publication

Breuer et al., 2026 - Chd7 regulates lipid metabolism and swim bladder inflation in zebrafish

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Fig. 4

Pparγ regulated lipid metabolism. A–D: Representative images for WISH of 5dpf chd7^+/+ and chd7^−/− larvae, including sense control, as well as results for RT-qPCR of key lipid genes in the swim bladder showing significant reduction for anxa5, fabp7b, elovl1 and pparγ at 5dpf. WISH (N = 3, n = 18–20 larvae for each staining) and RT-qPCR (N = 4 from 15 pooled fish per sample/genotype). Larvae for each experiment were taken from age-matched chd7^+/+ or chd7^−/− independent clutches (N = 3–4; significance: ∗P < 0.05; ∗∗P < 0.01; ∗∗∗P < 0.001; Error bars represent SD).

Expression Data

Genes:	anxa5b elovl1a fabp7b pparg
Fish:	WT chd7^{zf4383/zf4383}
Anatomical Terms:	swim bladder whole organism
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	chd7^{zf4383/zf4383}
Observed In:	swim bladder whole organism
Stage:	Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Lipid Res.