FIGURE

Figure 2

ID

ZDB-FIG-250627-46

Publication

Nguyen et al., 2025 - Cannabinoid Receptor 1 Regulates Zebrafish Renal Multiciliated Cell Development via cAMP Signaling

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Figure 2

cnr1 agonism leads to reduction in mature MCC population: (A) 28 ss WT, 0.01 mM MA and 0.01 mM AN-treated embryos stained via WISH using the mature MCC marker odf3b and cetn4; scale bar = 50 μm; (B,C) number of odf3b⁺ and cetn4⁺ cells per nephron at 28 ss; (D) 24 ss WT, 0.01 mM MA and 0.01 mM AN-treated embryos stained via WISH using the progenitor MCC marker pax2a and jag2b; scale bar = 50 μm; (E,F) number of pax2a⁺ and jag2b⁺ cells per nephron at 24 ss. Data presented on graphs are represented as mean ± SD; * p < 0.05 and **** p < 0.0001 (ANOVA).

Expression Data

Genes:	cetn4 cimap1b jag2b pax2a
Fish:	TU
Conditions:	chemical treatment by environment: anandamide chemical treatment by environment: Methanandamide
Anatomical Term:	ciliated cell
Stage Range:	20-25 somites to 26+ somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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