FIGURE

Fig. 5

ID

ZDB-FIG-250401-15

Publication

Zhang et al., 2024 - Morpho-histological and Transcriptome Analysis Reveal the Unreduced Sperm Formation Mechanism in cdk1-Depletion Zebrafish

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Fig. 5

Electron microscopic observation of WT and cdk1+/− zebrafish spermatogonia and transcriptome analysis of testis. A The ultrastructures of spermatogonia from WT and cdk1+/− zebrafish. Scale bar = 2 µm. B Measurement of spermatogonia diameter of WT and cdk1+/− zebrafish. C The numbers of up-regulated and down-regulated DEGs of cdk1+/− vs WT zebrafish. D KEGG pathway enrichment analysis of DEGs between WT and cdk1+/− zebrafish. E Expression heatmap of cell cycle-related genes. F Network interaction analysis of DEGs corresponding proteins. G Expression levels of Smc1a, Wee1, Smc3, Espl1, and Pp1 protein in the testes of WT and cdk1+/− zebrafish. cdk1, cyclin-dependent kinase 1; WT, wild-type zebrafish; cdk1+/−, zebrafish with heterozygous mutation of cdk1; DEGs, differentially expressed genes; KEGG, Kyoto Encyclopedia of Genes and Genomes

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	cdk1^zf4070/+ (AB)
Observed In:	spermatogonium
Stage:	Adult

Phenotype Detail

Acknowledgments

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