FIGURE

Figure 4

ID

ZDB-FIG-250215-56

Publication

Xia et al., 2025 - ctdsp2 Knockout Induces Zebrafish Craniofacial Dysplasia via p53 Signaling Activation

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Figure 4

(A–C) Phenotypes, (D–F) Sanger sequencing chromatograms, and (G–I) genotypes of F2 embryos. The F2 generation displayed two distinct phenotypic categories and three different genotypes: embryos without deformities had either wildtype or heterozygous ((−3+1) bp indels) genotypes, while those with deformities were exclusively homozygous for the (−3+1) bp indels. The red box denotes the sequence of gRNA (exon 1) (GGT TGT CTT CGA AAA CAG GT AGG), and the blue box indicates the 3 bp deletion sequence (GGT) and the 1 bp insert (A).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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