FIGURE

Fig. 1

ID
ZDB-FIG-250131-48
Publication
Li et al., 2024 - Dual effects of DLG5 (disks large homolog 5 gene) modulation on chemotherapy-induced thrombocytopenia and nausea/vomiting via the hippo signalling pathway
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Fig. 1

Over-expression of human DLG5 causes thrombocytes loss in zebrafish. (a–h) Gross morphology of Tg (CD41: GFP) zebrafish embryos at 3-dpf. Compared with control zebrafish (empty vector), human DLG5 over-expression (DLG5+) causes pericardial oedema (e, red arrowhead) and thrombocyte loss (g, h, yellow arrows). (i,j) Quantification of the average number of thrombocyte (GFP+) at caudal vein. Error bars, mean ± SEM.; *P < 0.05 (n = 10; Student's t test). dpf, days post fertilization.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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