FIGURE

Figure 6

ID

ZDB-FIG-250127-193

Publication

Ren et al., 2024 - Knockout of dhx38 Causes Inner Ear Developmental Defects in Zebrafish

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Figure 6

The abnormal splicing of genes involved inner ear development at 42 hpf: (A) The occurrence of an abnormal splicing event with IR and/or ES among genes associated with the development of the inner ear. (B) The statistical data of the PSI values at 42 hpf from three biological replicates. PSI, percent splicing in. (C) The downregulation of some genes with aberrant splicing in dhx38 mutants was detected using qRT-PCR at 42 hpf. The data are presented as the mean ± SD. ns, p > 0.05; *, p < 0.05; **, p < 0.01; ***, p < 0.001.

Expression Data

Genes:	cep290 col11a2 jag1b masp1 pax2a ret smad5 spns2
Fish:	WT dhx38^hzu20/hzu20
Anatomical Term:	whole organism
Stage:	High-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	dhx38^hzu20/hzu20
Observed In:	inner ear mRNA splicing, via endonucleolytic cleavage and ligation whole organism
Stage:	High-pec

Phenotype Detail

Acknowledgments

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