FIGURE

Fig. 7

ID

ZDB-FIG-240219-15

Publication

Murali et al., 2024 - Genetic variant classification by predicted protein structure: A case study on IRF6

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Fig. 7

A) Image of the AlphaFold2 prediction for IRF6, color coded by confidence score and the Predicted Aligned Error (PAE) from AlphaFold2 database. The color at position (x, y) indicates AlphaFold2’s expected position error at residue x, when the predicted and true structures are aligned on residue y. The PAE plot is useful for assessing the inter-domain accuracy of the predicted structure. Dark green indicates low error and light green indicates high error. Each of the squares corresponds to a domain. (B) Image of the AlphaFold2 prediction for GALC, color coded by confidence score and the Predicted Aligned Error (PAE) from AlphaFold2 database. These images were sourced directly from AlphaFold2 and the legend was adapted from AlphaFold2.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Comput Struct Biotechnol J