FIGURE

Fig. 6

ID

ZDB-FIG-240105-41

Publication

Jeong et al., 2024 - TMEM55B links autophagy flux, lysosomal repair, and TFE3 activation in response to oxidative stress

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Fig. 6

Depletion of TMEM55B reduces cell viability under oxidative stress conditions.

a Null and TMEM55B KO U2OS cells were treated with or without NaAsO₂ (300 μM) for 10 h. Cells were analyzed by Flow cytometry with Annexin V and 7AAD. 7AAD+ are necrotic, Annexin V+ are apoptotic and Annexin V + /7AAD+ are late apoptotic and necrotic cells. b Quantification of the population of live, necrotic (7AAD + ), apoptotic cells (Annexin V + ) and late apoptotic and necrotic cells (Annexin + /7AAD + ) from (a). The data represent means ± SEM, n = 3 independent experiments. Data taken from three independent experiments and statistical significance was determined by using two-way ANOVA with Sidak’s multiple comparisons. Source data are provided as a Source Data file.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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