FIGURE

Fig. 4

ID
ZDB-FIG-231215-80
Publication
Baker et al., 2022 - In Toto imaging of early enteric nervous system Development reveals that gut colonization is tied to proliferation downstream of ret
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Fig. 4

Generation of new ENCCs along the gut is compromised in retwmr1/+ fish. (A-D) ENCC proliferation produces successive generations of cells that migrate further than predecessors along the A-P axis of the gut tube. (A,B) ret+/+ ENCCs produce up to 18 generations to effectively colonize the entire gut tube (n=3). (C,D) retwmr1/+ ENCCs produce up to 13 generations that successively colonize the gut tube but fail to reach the hindgut (n=3). (E) Average number of cells per given generation are reduced in retwmr1/+ fish when compared with ret+/+. Data are mean±s.e.m. A, anterior; P, posterior.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Condition:
Observed In:
Stage Range: Long-pec to Protruding-mouth

Phenotype Detail
Acknowledgments
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