FIGURE

Fig. 8

ID
ZDB-FIG-231124-9
Publication
Wu et al., 2023 - Genetic evidence for differential functions of figla and nobox in zebrafish ovarian differentiation and folliculogenesis
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Fig. 8

A working model on differential roles of Figla and Nobox in zebrafish folliculogenesis.

Figla plays a critical role in controlling follicle formation in the event of cyst breakdown or follicle assembly, while Nobox is more involved in regulating follicle development after its formation, including such events as follicle activation (PG-PV transition) and vitellogenic growth (PV-EV transition). Nobox controls vitellogenic growth by regulating aromatase (cyp19a1a) expression in the follicle cells, which may be mediated by oocyte-secreted signaling molecules such as Gdf9 and Bmp15.

Expression Data

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Antibody Labeling
Phenotype Data

Phenotype Detail
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