IMAGE

Fig. 8

ID
ZDB-IMAGE-231124-9
Source
Figures for Wu et al., 2023
Image
Figure Caption

Fig. 8 A working model on differential roles of Figla and Nobox in zebrafish folliculogenesis.

Figla plays a critical role in controlling follicle formation in the event of cyst breakdown or follicle assembly, while Nobox is more involved in regulating follicle development after its formation, including such events as follicle activation (PG-PV transition) and vitellogenic growth (PV-EV transition). Nobox controls vitellogenic growth by regulating aromatase (cyp19a1a) expression in the follicle cells, which may be mediated by oocyte-secreted signaling molecules such as Gdf9 and Bmp15.

Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Commun Biol