FIGURE

FIGURE 11

ID
ZDB-FIG-231002-236
Publication
Meier et al., 2023 - Zebrafish as model system for the biological characterization of CK1 inhibitors
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FIGURE 11

Representative pictures of hearts of inhibitor-treated and csnk1d MO injected embryos. Embryos were either treated with DMSO, 10 µM G2-2 or 10 µM G2-3 for 48 h from 24 hpf, or injected with csnk1da, csnk1db or control Morpholino (Std Ctr). DMSO and Std Ctr MO had wildtype heart morphology and function. Treatment with 10 µM G2-2 and G2-3 as well as injection of 400 µM csnk1da or 300 µM csnk1db Morpholino resulted in reduced heart function (n = 30 for each compound and morpholino).

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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