FIGURE

Fig. 5

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ZDB-FIG-230226-44

Publication

Vorontsova et al., 2022 - In vivo macromolecular crowding is differentially modulated by aquaporin 0 in zebrafish lens: Insights from a nanoenvironment sensor and spectral imaging

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Fig. 5

Disruption of DR distribution in Aqp0 mutant lenses.

(A) Examples of DR images of lenses at 4 dpf of WT and mutants. Scale bars, 20 μm. (B) DR radial profiles (n = 54). (C) Radial lens position of the maximal DR values are shown as function of distance into the lens, where r is the distance from lens center and a is the lens radius. (D) Mean DR of the whole equatorial lens plane (D1), epithelium (D2), outer cortex (D3), inner cortex (D4), and nucleus (D5) of the lens as indicated by the insets. See table S3 for a summary of n numbers. See fig. S8 for ACDAN intensity images, spectral phasor plots, and DR images for examples shown in (A). Statistical significance was denoted with * at a significance level P < 0.05 and ** at a significance level P < 0.005.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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