FIGURE

Fig. 4

ID

ZDB-FIG-230107-7

Publication

Rösch et al., 2022 - ERBB and P-glycoprotein inhibitors break resistance in relapsed neuroblastoma models through P-glycoprotein

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Fig. 4

ABCB1 is upregulated in neuroblastoma relapsed tumors. (A) Gene expression data of 18 tumor samples from the dataset by Schramm et al. (GSE65303) were downloaded from R2 (http://r2.amc.nl, 09 September 2021). Only paired samples with data at primary diagnosis (tumor) and at relapse were included (n = 7 pairs). Statistics of log‐transformed relapse values were calculated with Student's t test against 0. (B) Gene expression data from the INFORM registry (n = 1645). Comparison of neuroblastoma cases (n = 162) vs. all other entities. Statistics were calculated by ANOVA followed by Tukey's post‐test including all genes of the ERBB and ABC families present in the respective datasets.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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