FIGURE

FIG 8

ID

ZDB-FIG-221226-30

Publication

Choi et al., 2022 - Neuromasts and Olfactory Organs of Zebrafish Larvae Represent Possible Sites of SARS-CoV-2 Pseudovirus Host Cell Entry

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FIG 8

Schematic illustrations to show the suggested mechanism of PEG-pseudovirus entry into the anterior neuromasts of zebrafish larvae. (A) Structure of a neuromast. The regions bounded by the black and red rectangles are shown at higher magnification in panels B and C, respectively. (B) Proposed endocytic pathway illustrating the localization of TPCs (both TPC1 and TPC2) on different endolysosomal compartments and the location of bafilomycin A1 inhibition. (C) Proposed endocytic mechanism in the anterior neuromasts of (a) DMSO-treated (control) and (b) bafilomycin A1-treated larvae, after incubation with Alexa Fluor 488-dextran (green). Panel A was modified from reference 155 with permission of Elsevier, and panel B was modified from reference 156 with permission of the Federation of European Biochemical Societies.

Expression Data

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Antibody Labeling

Phenotype Data

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Virol.