FIGURE

Fig. 3

ID
ZDB-FIG-220513-52
Publication
Leibold et al., 2022 - Long-term obesogenic diet leads to metabolic phenotypes which are not exacerbated by catch-up growth in zebrafish
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Fig. 3

Fig 3. Fish undergoing CR and CG are hyperphagic.

(A) agrp expression analysis of CR and DIO fish brains as well as CG9 fish brains 1–2 weeks after the shift to the obesogenic environment. Expression is standardized to rps23; (B) calorically restricted fish are severely hyperphagic when exposed to ad libitum feeding conditions compared to the DIO group that has been raised in an obesogenic environment; (C) CG3 fish are hyperphagic before (CR) transfer to DIO conditions as well as at least one week after transfer (CG3); (D) The CG9 group is similarly hyperphagic before as well as at least one week after the transfer to DIO conditions. Pooled data of male and female fish, n of 4–10; error bars indicate STDEV, groups were compared with ANOVA followed by Tukey’s multiple comparisons test (A) or an unpaired t-test (C, D), significance is indicated as * p<0.05, ** p<0.01 and *** p<0.001.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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