FIGURE

Figure 6

ID
ZDB-FIG-220430-85
Publication
Lin et al., 2022 - Cerebroventricular Injection of Pgk1 Attenuates MPTP-Induced Neuronal Toxicity in Dopaminergic Cells in Zebrafish Brain in a Glycolysis-Independent Manner
Other Figures
All Figure Page
Back to All Figure Page
Figure 6

Figure 6. Direct injection of Pgk1 into the brain of adult zebrafish alleviates the impairment of swimming performance induced by MPTP. (A) Schematic diagram to illustrate the timetable of the six-month-old adult zebrafish being treated with intraperitoneal injections of MPTP, combined with a brain injection of Pgk1, followed by behavioral analysis. (B) Statistical analysis of total swimming distance (in cm) of adult fish treated with different concentrations of MPTP, as indicated, combined with, or without, a Pgk1 injection. The total swimming distance was averaged from three independent trials, and the distance of each trial was averaged from five adult fish, while the distance of a single fish sample was averaged from three touches. Student’s t-test was used to determine significant differences between each group (***, p < 0.001; *, p < 0.05).

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.