Fig. 5

a Mapping onto the Constellations plot of transcription factors with correlated gene body activity and DNA-binding motif enrichment in specific clusters. Sizes of circles denote correlation of peak module mapping to motifs, and red color to gene body activities. b Top peak modules for hyaline cartilage and dermal fibroblast 1 clusters at 14 dpf mapped onto 14 dpf and 1.5 dpf SnapATAC UMAPs. c Summed gene body activities of foxc1a, foxc1b, foxf1, foxf2a, and foxf2b and summed FOXC1, FOXF1, and FOXF2 motifs at 1.5 dpf correlate with cartilage peak mapping, and lef1 gene body activity and LEF1 motif with dermal fibroblast peak mapping. d, e Retrograde cartilage accessibility mapping at 1.5 dpf allows predictions of the arch origins of the individual cartilaginous elements of the week-old skeleton: ceratobranchials (CBs), ceratohyal (CH), ethmoid (ET), hyomandibula (HM), Meckel’s (M), palatoquadrate (PQ), symplectic (SY), and trabecula (TR). f Mapping of the top peak module for 14 dpf gill progenitor clusters onto 5 dpf SnapATAC UMAP shows correlation with gata3 gene body activity and GATA3 motif.