FIGURE

Fig. 8

ID

ZDB-FIG-210813-28

Publication

Topel et al., 2020 - lncRNA HOTAIR overexpression induced downregulation of c-Met signaling promotes hybrid epithelial/mesenchymal phenotype in hepatocellular carcinoma cells

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Fig. 8

Bioinformatic analyses of GEO and TCGA datasets supports HOTAIR and c-Met interplay. (a) Column graph of c-Met protein expression in control-siRNA and HOTAIR-siRNA transfected HepG2 cells in GEO dataset GSE98091. (b) MET gene expression in experimental groups of GEO dataset GSE109483. Column graphs of control-GapMeR and HOTAIR-GapmeR transfected Ewing sarcoma cell lines ES2, A673 and SK-ES (1st, 2nd and 3rd graphs). Last graph belongs to hTERT-immortalized human mesenchymal stem cells (hMSC), hMSCs transfected with GFP (hTERT-GFP) and HOTAIR-GFP (hTERT-GFP-HOTAIR) overexpression vectors. Analysis of (c) MET (d) HOTAIR gene expressions in TCGA datasets. (e) Heatmap of gene expression correlation analysis of HOTAIR and MET in TCGA datasets. GEO dataset analysis are performed with GREIN and TCGA gene expression and correlation analysis are performed with LncTarD. * p ≤ 0.05

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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