FIGURE

FIGURE 3

ID

ZDB-FIG-210428-49

Publication

Dasgupta et al., 2021 - Phenotypically Anchored mRNA and miRNA Expression Profiling in Zebrafish Reveals Flame Retardant Chemical Toxicity Networks

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FIGURE 3

Major gene ontology (GO) processes across FRCs based on (A) differentially expressed mRNAs and (B) target mRNAs of differentially expressed miRs. GO was analyzed using human orthologs within Metacore. For panel (B), differentially expressed miRs were imported into TFmiR and both experimentally validated, and computationally predicted gene targets were imported into Metacore for GO analysis. Data is represented as -log (FDR p value) for each term; a value of ∼1.3 represents FDR p threshold of 0.05. Numbers within cells represent the significant -log (FDR p value). (C) Expression of representative mRNAs known to regulate nervous system development and neurotransmitter activity. Horizontal lines with numbers (1–7) represent FRC class based on Figure 1.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol