FIGURE

Figure 2

ID

ZDB-FIG-200824-9

Publication

Ito et al., 2020 - Identification of the hypertension drug niflumic acid as a glycine receptor inhibitor

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Figure 2

Heteromeric GlyR decreased glycine sensitivity compared with homomeric GlyR. (a) A trace of two-electrode voltage-clamp recording from oocyte injected with five femtomoles of zGlyRα1 cRNAs exposed to serial application of glycine of increasing amounts. (b) Cumulative concentration–response relationship of glycine-evoked currents. The amplitude of glycine-evoked currents was normalized to the maximally-evoked current as 100% for each oocyte (n = 10). Values here and elsewhere represent mean ± SEM.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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