FIGURE

Figure 14

ID

ZDB-FIG-200716-67

Publication

Keller et al., 2020 - Validating the Paradigm That Biomechanical Forces Regulate Embryonic Cardiovascular Morphogenesis and Are Fundamental in the Etiology of Congenital Heart Disease

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Figure 14

Increased arterial load via unilateral vitelline artery ligation (VAL) alters aortic structural properties. Representative images of VAL (A,C,E,G,I) and control (B,D,F,H,J) dorsal aortas stained with hematoxylin and eosin (A,B), and antibodies against smooth muscle α-actin (C,D), collagen type III (E,F), procollagen type I (G,H), and antibody M38 (I,J) show increased content in dorsal aorta and perivascular tissues in VAL embryos. Magnification is × 600 and scale bars are 20 µm for A–F, and × 200 and 50 µm, respectively, for G–J. This was adapted with permission [221].

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This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J Cardiovasc Dev Dis