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Figure 11

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ZDB-FIG-200716-64
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Keller et al., 2020 - Validating the Paradigm That Biomechanical Forces Regulate Embryonic Cardiovascular Morphogenesis and Are Fundamental in the Etiology of Congenital Heart Disease
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Figure 11

Aortic arch morphogenesis and flow modeling. (A) Representative mean flow path-lines using realistic geometries from micro-CT casts, fluorescent ink injections in a stage 18 chick embryo. Note that flow stream separation occurs through the aortic sac, arches, and dorsal aorta. (B) Representative mean flow path-lines using realistic geometries from micro-CT casts, fluorescent ink injections in a stage 24 chick embryo with similar flow stream separation. (C) Aortic sac and arch wall shear stress distributions at stage 18 for the left lateral (L) and right lateral (R) views. (D) Aortic sac and arch wall shear stress distributions at stage 24. This was adapted with permission [161].

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This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J Cardiovasc Dev Dis