FIGURE

Fig. 2

ID

ZDB-FIG-200614-4

Publication

Castro et al., 2020 - Hcfc1a regulates neural precursor proliferation and asxl1 expression in the developing brain

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Fig. 2

The hcfc1a^co60/+ allele increases the number of Sox2⁺ cells in the developing brain. a Quantitative real time PCR analyzing the relative expression of sox2 and pax6 in wildtype siblings (Sibling) and the hcfc1a^co60/+ allele (Co60/+). N = 7 larvae per group/biological replicate *p < 0.05. b–d Quantification of the number of Sox2⁺ cells at 1 day post fertilization (DPF) (b), 2 DPF (c), and 5 DPF (d) in the early forebrain (EF), forebrain (FB), midbrain (MB), and hindbrain (HB). *p = 0.006828, **p = 1.13873E−05, ***p = 0.000107, ^#p = 0.010168, ^##p = 4.55E−06, ^###p = 1.97E−07, and ^§p = 0.005476. In b total number of animals is Sibling (N = 6) and hcfc1a^co60/+ (N = 6), c total animals is Sibling (N = 7) and hcfc1a^co60/+ (N = 7), and d total animals is Sibling (N = 4) and hcfc1a^co60/+ (N = 4). All error bars represent standard error of the mean

Expression Data

Gene:	sox2
Fish:	WT hcfc1a^co60/+
Anatomical Term:	whole organism
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	hcfc1a^co60/+
Observed In:	forebrain neuronal stem cell hindbrain neuronal stem cell midbrain neuronal stem cell neuronal stem cell whole organism
Stage Range:	Prim-5 to Day 5

Phenotype Detail

Acknowledgments

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