ZFIN ID: ZDB-FIG-190627-34
Yildiz et al., 2019 - Zebrafish prdm12b acts independently of nkx6.1 repression to promote eng1b expression in the neural tube p1 domain. Neural Development   14:5 Full text @ Neural Dev.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Antibodies:
Fish:
Anatomical Terms:
Stage: Day 4
PHENOTYPE:
Fish:
Observed In:
Stage: Day 4

Fig. 3

prdm12b mutant fish display an abnormal touch evoked response. a-d. Representative kinematic traces for 10 wildtype (a) and 11 prdm12b mutant (b) fish stimulated with a head touch, as well as for 11 prdm12b mutants first assayed with a head touch (c) and subsequently with a tail touch (d). Zero degrees on the y-axis indicate a straight body while positive and negative angles represent body bends in opposite directions. All fish were at 4dpf. e. Anti-3A10 labeling of Mauthner neurons in a cross of prdm12b+/um318 heterozygotes (n = 117). f. Anti-F310 labeling of somites in a cross of prdm12b+/um398 heterozygotes (n = 16)

Gene Expression Details No data available
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
Ab-3A10 IHC WT standard conditions Day 4 Mauthner neuron
IHC prdm12bum318/um318 standard conditions Day 4 Mauthner neuron
Ab-F310 IHC WT standard conditions Day 4 trunk musculature
IHC prdm12bum318/um318 standard conditions Day 4 trunk musculature
Phenotype Details
Fish Conditions Stage Phenotype
prdm12bum318/um318 standard conditions Day 4 Mauthner neuron morphology, normal
Day 4 thigmotaxis process quality, abnormal
Day 4 trunk musculature morphology, normal
prdm12bum319/um319 standard conditions Day 4 thigmotaxis process quality, abnormal
Acknowledgments:
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