FIGURE
Fig. S3
- ID
- ZDB-FIG-180827-72
- Publication
- Daane et al., 2018 - Bioelectric-calcineurin signaling module regulates allometric growth and size of the zebrafish fin
- Other Figures
- All Figure Page
- Back to All Figure Page
Fig. S3
Deletion screen of kcnk5b reveals essential role of C-terminus. Using specific guide RNAs against the last exon of knck5b encoding the last transmembrane and cytoplasmic tail of the channel, we screened injected founders for evidence of overgrowth. We identified localized clones having specific overgrowth of the fins. B) Analysis of the changes in the overgrown tissues demonstrated presence of local deletions in kcnk5b predicted to cause truncation of the channel in a comparable location as to the alf mutation (C). |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ Sci. Rep.