FIGURE

Fig. 5

ID

ZDB-FIG-171110-20

Publication

Chang et al., 2016 - Sodium Selenite Acts as an Otoprotectant against Neomycin-Induced Hair Cell Damage in a Zebrafish Model

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Fig. 5

Scanning electron microscopy (SEM, O1, x 10K).

The kinocilium (K) and the stereocilia bundles (asterisk) of hair cells in neuromast were clearly visible in the negative control (A). However, when the 5-dpf transgenic zebrafish were treated with 125μM neomycin for 1 h, the kinocilium and the stereocilia bundles were affected and severely disrupted (B). Sodium selenite provided nearly complete protection against neomycin-induced the damage of the kinocilium (K) and the stereocilia bundles (asterisk) in the neuromasts (C). Images were obtained in three 5-dpf zebrafish for each group. Scale bar (at the bottom of each figure, one space) = 3 μm. NM, neomycin; S, sodium selenite.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	s356tTg
Conditions:	chemical treatment by environment: neomycin chemical treatment by environment: neomycin
Observed In:	neuromast kinocilium neuromast stereocilium
Stage:	Day 5

Phenotype Detail

Acknowledgments

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