ZFIN ID: ZDB-FIG-170210-3
Wang et al., 2016 - The somite-secreted factor Maeg promotes zebrafish embryonic angiogenesis. Oncotarget   7(47):77749-77763 Full text @ Oncotarget
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Knockdown Reagent:
Anatomical Terms:
Stage: Prim-15
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage Range: Prim-5 to Prim-15

Fig. 3

maeg loss of function results in the blood vessel morphogenesis defects in zebrafish embryos. A. Confocal imaging analysis of trunk vascular and somital morphology in WT, maeg−/− and maeg morphants Tg(kdrl:EGFP) embryos at 30 hpf. Red and white square brackets indicate the lumen of the DA and PCV, respectively. DA, dorsal aorta; PCV, posterior cardinal vein; and DLAV, dorsal longitudinal anastomotic vessel. B. The statistics of ISV length in WT, maeg−/− and maeg morphants. One-Way ANOVA; ***,P<0.001. C. The statistics of DA and PCV lumen size at 30 hpf. Error bars indicate stdev.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
EGFP egfl6zf774/zf774; s843Tg standard conditions Prim-15 dorsal aorta IHC
Prim-15 intersegmental vessel IHC
Prim-15 posterior cardinal vein IHC
s843Tg standard conditions Prim-15 dorsal aorta IHC
Prim-15 intersegmental vessel IHC
Prim-15 posterior cardinal vein IHC
s843Tg + MO1-egfl6 standard conditions Prim-15 dorsal aorta IHC
Prim-15 intersegmental vessel IHC
Prim-15 posterior cardinal vein IHC
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
egfl6zf774/zf774; s843Tg standard conditions Prim-5 intersegmental vessel decreased length, abnormal
Prim-5 sprouting angiogenesis decreased occurrence, abnormal
Prim-15 dorsal longitudinal anastomotic vessel blood vessel morphogenesis decreased occurrence, abnormal
Prim-15 intersegmental vessel decreased length, abnormal
Prim-15 sprouting angiogenesis decreased occurrence, abnormal
s843Tg + MO1-egfl6 standard conditions Prim-5 intersegmental vessel decreased length, abnormal
Prim-5 sprouting angiogenesis decreased occurrence, abnormal
Prim-15 dorsal longitudinal anastomotic vessel blood vessel morphogenesis decreased occurrence, abnormal
Prim-15 intersegmental vessel decreased length, abnormal
Prim-15 sprouting angiogenesis decreased occurrence, abnormal
Acknowledgments:
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Oncotarget