FIGURE

Fig. 5

ID
ZDB-FIG-161019-8
Publication
Ellis et al., 2016 - Experimental Dissection of Metalloproteinase Inhibition-Mediated and Toxic Effects of Phenanthroline on Zebrafish Development
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Fig. 5

PhN disrupts craniofacial neural crest. (A) Epifluorescence micrograph of the head of a 48 hpf Tg(sox10a:eGFP) embryo treated from 24 hpf with 10 µM PhE showing normal development of the craniofacial neural crest (arrowheads indicate the otic vesicle and jaw cartilage). Embryos treated with: (B) 5; (C) 10; (D) 25; and (E) 40 µM PhN, exhibiting progressively more severe defects in these structures. Arrowhead in (E) indicates presumptive pigment cells trapped below the epidermis. Scale bars are 200 µm.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
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