FIGURE

Fig. S12

ID
ZDB-FIG-160311-32
Publication
Guo et al., 2016 - Functional Investigation of a Non-coding Variant Associated with Adolescent Idiopathic Scoliosis in Zebrafish: Elevated Expression of the Ladybird Homeobox Gene Causes Body Axis Deformation
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Fig. S12

Notochord deformity and displaced dorsal melanophore stripe in embryos with lbx1b expressed under the control of the GATA2 minimal promoter and an lbx1b enhancer.

(A) Lateral views of embryos (48 hpf) injected with GATA2-1b:mCherry (ctrl) or GATA2-1b:lbx1b (lbx1b). Local notochord deformation (red arrow) was observed in lbx1b embryos. The lower panels show magnified views of the areas indicated by the dotted boxes in the corresponding middle panels. Scale bars represent 500 µm. (B) Quantitative analysis of the phenotypes of notochord deformation (nc+) and displaced dorsal melanophore stripe (str+) in 6 dpf zebrafish (ctrl, n = 224; lbx1b, n = 288).

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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