FIGURE

Fig. S6

ID
ZDB-FIG-160311-26
Publication
Guo et al., 2016 - Functional Investigation of a Non-coding Variant Associated with Adolescent Idiopathic Scoliosis in Zebrafish: Elevated Expression of the Ladybird Homeobox Gene Causes Body Axis Deformation
Other Figures
All Figure Page
Back to All Figure Page
Fig. S6

Normal dorsoventral patterning in embryos with lbx1b overexpression.

(A) Whole-mount in situ hybridization (WISH) for dorsal organizer gene chd and ventral gene vox in shield-stage embryos injected with buffer as control (ctrl) or lbx1b mRNA (lbx1b). Photos are taken from the animal pole side of embryos with dorsal to the left. (B) Quantitative analysis of the WISH signals shown in A. For quantification of the dorsoventral position, the angle θ [degree] shown in the panel A as measured. No significant change was observed for both chd (p = 0.261) and vox (p = 0.071) expression pattern. The numbers of control and lbx1b zebrafish embryos were 22 and 23 for chd, 23 and 23 for vox, respectively.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Genet.